The writer Nathan Zuckerman comes down with a mysterious physical affliction - pure pain, beginning in his neck and shoulders, invading his torso, and taking possession of his life. Zuckerman, whoses work was his life, is unable to write a line. Now his work is trekking from one doctor to the next - from orthopaedist to osteopath to neurologist to psychiatrist - but none can find a cause for the pain and nobody can assuage it...THE ANATOMY LESSON is one of Roth's finest achievements - a comic masterpiece and brilliant finale to the Zuckerman trilogy.