Chapter 1 - Searching for a solution method for the Smart Waste Collection Routing Problem, Ana Raquel Aguiar, Carolina Soares de Morais, (*)Tânia Rodrigues Pereira Ramos and Ana Paula Barbosa-Póvoa Chapter 2 - A multi-objective and multi-period model to the design and operation of a hydrogen supply chain: an applied case in Portugal, Diego Câmara, Tânia Pinto-Varela and Ana Paula Barbosa-Póvoa Chapter 3 - The E-constrained method to solve a bi-objective problem of sustainable cultivation, Angelo Aliano Filho and Helenice Florentino Silva Chapter 4 - In-house logistics operations enhancement in the automobile industry using simulation, Rodrigo Macedo, Fábio Coelho, (*)Susana Relvas and Ana Barbosa-Póvoa Chapter 5 - The rough interval shortest path problem, Ali Moghanni and Marta Pascoal Chapter 6 - Reinforcement Learning for Robust Optimization: an Application in Kidney Exchange Programs, Tiago Monteiro, João Pedro Pedroso, Ana Viana and Xenia Klimentova Chapter 7 - Facing dynamic demand for surgeries in a Portuguese case study, Mariana Oliveira and Inês Marques Chapter 8 - Adaptive Sequence-based Heuristic for Two-Dimensional Non-Guillotine Packing Problems, Óscar Oliveira, Dorabela Gamboa and Elsa Silva Chapter 9 - A CVRP Model for an In-plant Milk Run System, M. Teresa Pereira, Cristina Lopes, Luís Pinto Ferreira and Silvana Oliveira Chapter 10 - Merging Resilience and Sustainability in Supply Chain Design, João Pires Ribeiro, Bruna Mota and Ana Barbosa-Póvoa Chapter 11 - Analysis and Optimisation of a Production Line Using Discrete Simulation, Fabiane K. Setti, Carla A. S. Geraldes, João P. Almeida and Marcelo G. Trentin Chapter 12 - Design and Planning of Green Supply Chains with Risk Concerns, Cátia da Silva, Ana Carvalho and Ana Barbosa-Póvoa Chapter 13 - Benchmarking Smart Grid Research & Development engagement by European Distribution System Operators, Micael Simões, Rogério Rocha and Ana Camanho Chapter 14 - Towards an integrated decision-support framework for the new generation of manufacturing systems, Miguel Vieira, Fábio Coelho, Cátia da Silva, Bruna Mota, Joana Guapo, Rodrigo Macedo, Bruno Gonçalves, Samuel Moniz, Tânia Pinto-Varela, Ana Carvalho, Susana Relvas and Ana P. Barbosa-Póvoa