Once in a while a novel comes along that is very different. House of Large Sizes is such a novel. A dysfunctional, sexually addicted and inauthentic little family finds its failings coming to a head when one member decides to deal with his pain directly and heads to New Orleans for an unsanctioned sex change. They all end up in The French Quarter-in "The sump of America"-and a great mythic Jambalaya of horrors are visited upon them as a venomous and self-professed witch threatens to run amok. House of Large Sizes is a rare but extraordinarily "readable" literary work, which draws from multiple genres to produce its sometimes shocking and laser-like effect on the imagination.