This book describes community ophthalmology professionals in South Asia who exemplify social entrepreneurship in global health to help the rural poor. With the World Health Organization, they built a network to reduce and control blindness and then created a cross-subsidization finance model to support their efforts. They reinvented surgical techniques, adopted high technology as appropriate technology, and trained other ophthalmology professionals to use their systems approach. The end result is that their innovations spread from India and Nepal outwards to other countries in Africa and Asia, as well as the United States, Australia, and Finland. This involved contesting economic and scientific norms.This feminist postcolonial global ethnography demonstrates that their innovations have created dual socio-technical systems to solve the problem of avoidable blindness. Policymakers now have an example of how to avoid Schumacher's critique of low labor, large scale and implement Gandhi's philosophy of good for all.